Fist-Sized Blood Filter

This page is the CodyCross answer for the clue below from Time for a check-up, Group 1708, Puzzle 4 (Electrolytes).

Question is: Fist-Sized Blood Filter

and the answer is: SPLEEN

Word Meaning:

SPLEEN — (anatomy, immunology) In vertebrates, including humans, a ductless vascular gland, located in the left upper abdomen near the stomach, which destroys old red blood cells, removes debris from the bloodstream, acts as a reservoir of blood, and produces lymphocytes.

Definitions from Wiktionary.