General Unhappiness With Life

This page is the CodyCross answer for the clue below from Concert Hall, Group 598, Puzzle 4 (Wolfgang Amadeus Mozart).

Question is: General Unhappiness With Life

and the answer is: DYSPHORIA

Word Meaning:

DYSPHORIA — A state of feeling unwell or unhappy; a feeling of emotional and mental discomfort and suffering from restlessness, malaise, depression, or anxiety.

Definitions from Wiktionary.