Harmful; Anagram of Evaders

Puzzle 2 of Tolkien Universe Medium Pack

Question is: Harmful; Anagram of Evaders

and the answer is: ADVERSE

Word Meaning:

ADVERSE — Unfavorable; antagonistic in purpose or effect; hostile; actively opposing one's interests or wishes; contrary to one's welfare; acting against; working in an opposing direction.

Definitions from Wiktionary.