How to Lose Friends & __ People, Simon Pegg Film

This page is the CodyCross answer for the clue below from World of Sounds, Group 1350, Puzzle 3 (Sonic Acupuncture).

Question is: How to Lose Friends & __ People, Simon Pegg Film

and the answer is: ALIENATE

Word Meaning:

ALIENATE — (archaic, followed by "from") Estranged; withdrawn in affection; foreign

Definitions from Wiktionary.