Lose __; Tire, Fade, Weaken
This page is the CodyCross answer for the clue below from London, Group 498, Puzzle 2 (Kensington Palace).
Question is: Lose __; Tire, Fade, Weaken
and the answer is: ENERGY
Word Meaning:
ENERGY — The impetus behind all motion and all activity.
Definitions from Wiktionary.