Necrosis of Human Tissue Leading to Amputation

This page is the CodyCross answer for the clue below from Train Travel, Group 703, Puzzle 5 (Rail Network).

Question is: Necrosis of Human Tissue Leading to Amputation

and the answer is: GANGRENE

Word Meaning:

GANGRENE — The necrosis and rotting of flesh, usually caused by lack of blood supply.

Definitions from Wiktionary.

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