Organ __ Is the Shut Down of Essential Organs

This page is the CodyCross answer for the clue below from Transport, Group 101, Puzzle 3.

Question is: Organ __ Is the Shut Down of Essential Organs

and the answer is: FAILURE

Word Meaning:

FAILURE — State or condition of not meeting a desirable or intended objective, opposite of success.

Definitions from Wiktionary.