Panic, Lose Control
This page is the CodyCross answer for the clue below from London, Group 490, Puzzle 1 (Globe Theatre).
Question is: Panic, Lose Control
and the answer is: FREAKOUT
Word Meaning:
FREAK OUT — (dated slang) A negative or unpleasant experience with LSD or another psychedelic drug.
Definitions from Wiktionary.