Progenitor, E.g. Great-Grandparent
Puzzle 17 of Day of the Dead Hard Pack
Question is: Progenitor, E.g. Great-Grandparent
and the answer is: ANCESTOR
Word Meaning:
ANCESTOR — One from whom a person is descended, whether on the father's or mother's side, at any distance of time; a progenitor; a forefather; a forebear.
Definitions from Wiktionary.