Space Within the Cytoplasm of a Cell

This page is the CodyCross answer for the clue below from Architectural Styles, Group 1177, Puzzle 3 (Empire State Building).

Question is: Space Within the Cytoplasm of a Cell

and the answer is: VACUOLE

Word Meaning:

VACUOLE — (cytology) A large membrane-bound vesicle in a cell's cytoplasm.

Definitions from Wiktionary.