The Oil in Poison Ivy That Causes a Rash

Puzzle 20 of Tolkien Universe Medium Pack

Question is: The Oil in Poison Ivy That Causes a Rash

and the answer is: URUSHIOL

Word Meaning:

URUSHIOL — (organic chemistry) An oil found in plants of the family Anacardiaceae, causing an allergic skin rash on contact; consists of a variable mixture of several related organic compounds.

Definitions from Wiktionary.