The Son of Your Brother or Sister
Puzzle 14 of Housewarming Gifts Pack
Question is: The Son of Your Brother or Sister
and the answer is: NEPHEW
Word Meaning:
NEPHEW — A son of one's sibling, brother-in-law, or sister-in-law; either a son of one's brother (fraternal nephew) or a son of one's sister (sororal nephew).
Definitions from Wiktionary.